Liquid Biopsy and the Principle of Non-maleficence: Ethical Challenges for Medical Practice and training

Abstract

Introduction: Liquid biopsy has emerged as an innovative diagnostic tool that allows diseases such as cancer to be detected and monitored through the analysis of bodily fluids. Although it represents a significant advance because it is less invasive and more accessible for clinical monitoring, its use raises important ethical challenges, especially from the perspective of the principle of non-maleficence.

Objective: To reflect on the ethical challenges posed by the use of liquid biopsy in relation to the principle of non-maleficence in clinical practice and medical training.

Author's position: The implementation of this technique must be guided by an ethic of care that puts the well-being of the patient before the fascination with technological innovation. Likewise, the need to strengthen medical education in bioethics is emphasized, so that future health professionals are prepared to face the ethical dilemmas arising from the application of new technologies. Medical training should include content that promotes critical thinking, prudent clinical judgment, and empathetic communication.

Conclusions: The use of liquid biopsy requires a comprehensive approach that combines technical knowledge, ethical judgment, and human sensitivity. Only in this way will it be possible to ensure that advances in medicine do not cause harm and are geared toward improving patients' quality of life, from a responsible perspective, both clinically and educationally.